绵羊季节性繁殖的神经内分泌研究进展

doi:10.11843/j.issn.0366-6964.2018.01.003

Abstract

Abstract:

Seasonal reproduction is a common adaptive strategy that allows for breeding at times when it is most advantageous for survival and growth of offspring, a major reason for seasonal reproduction is a striking change in the responsiveness of gonadotropin-releasing hormone (GnRH) neurons to the negative feedback effects of estradiol. In recent years, the neural and neuroendocrine circuitry responsible for sheep seasonal reproduction has been primarily studied, which concerned with the melatonin action and changes of the relevant neuron activities in hypothalamus. In this review, we first described the afferent signals, neural circuitry for seasonal reproductive transitions in sheep, and then compared these mechanisms with those discovered from studies in hamsters. These results can provide reference for the study of neural mechanisms controlling seasonal reproduction in sheep.

CLC Number:

S826.2

HE Xiao-yun, DI Ran, HU Wen-ping, WANG Xiang-yu, LIU Qiu-yue, CHU Ming-xing. Research Progress on Neuroendocrinology Controlling Sheep Seasonal Reproduction[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2018, 49(1): 18-25.

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References

[1] LINCOLN G A, SHORT R V. Seasonal breeding:nature's contraceptive[J]. Recent Prog Horm Res, 1980, 36:1-52.
[2] ALFONZO J. Estrogen receptors involved in the differential regulation of hypothalamic kisspeptin expression[D]. Corvallis:University of Oregon State, 2016.
[3] KARSCH F J, BITTMAN E L, FOSTER D L, et al. Neuroendocrine basis of seasonal reproduction[J]. Recent Prog Horm Res, 1984, 40:185-232.
[4] LYNCH E W J, COYLE C S, STEVENSON T J. Photoperiodic and ovarian steroid regulation of histone deacetylase 1, 2, and 3 in Siberian hamster (Phodopus sungorus) reproductive tissues[J]. Gen Comp Endocrinol, 2017, 246:194-199.
[5] HENNINGSEN J B, ANCEL C, MIKKELSEN J D, et al. Roles of RFRP-3 in the daily and seasonal regulation of reproductive activity in female Syrian hamsters[J]. Endocrinology, 2017, 158(3):652-663.
[6] KARSCH F J, GOODMAN R L, LEGAN S J. Feedback basis of seasonal breeding:test of an hypothesis[J]. J Reprod Fertil, 1980, 58(2):521-535.
[7] BITTMAN E L, KARSCH F J, HOPKINS J W. Role of the pineal gland in ovine photoperiodism:regulation of seasonal breeding and negative feedback effects of estradiol upon luteinizing hormone secretion[J]. Endocrinology, 1983, 113(1):329-336.
[8] WOODFILL C J I, WAYNE N L, MOENTER S M, et al. Photoperiodic synchronization of a circannual reproductive rhythm in sheep:identification of season-specific time cues[J]. Biol Reprod, 1994, 50(4):965-976.
[9] THIERY J C, MALPAUX B. Seasonal regulation of reproductive activity in sheep:modulation of access of sex steroids to the brain[J]. Ann N Y Acad Sci, 2003, 1007:169-175.
[10] WEAVER D R, RIVKEES S A, REPPERT S M. Localization and characterization of melatonin receptors in rodent brain by in vitro autoradiography[J]. J Neurosci, 1989, 9(7):2581-2590.
[11] BITTMAN E L, DEMPSEY R J, KARSCH F J. Pineal melatonin secretion drives the reproductive response to daylength in the ewe[J]. Endocrinology, 2013, 113(6):2276-2283.
[12] JOHNSTON J D, SKENE D J. 60 years of neuroendocrinology:regulation of mammalian neuroendocrine physiology and rhythms by melatonin[J]. J Endocrinol, 2015, 226(2):T187-T198.
[13] WEEMS P W, GOODMAN R L, LEHMAN M N. Neural mechanisms controlling seasonal reproduction:principles derived from the sheep model and its comparison with hamsters[J]. Front Neuroendocrinol, 2015, 37:43-51.
[14] MALPAUX B, MIGAUD M, TRICOIRE H, et al. Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin[J]. J Biol Rhythms, 2001, 16(4):336-347.
[15] MALPAUX B, DAVEAU A, MAURICE-MANDON F, et al. Evidence that melatonin acts in the premammillary hypothalamic area to control reproduction in the ewe:presence of binding sites and stimulation of luteinizing hormone secretion by in situ microimplant delivery[J]. Endocrinology, 1998, 139(4):1508-1516.
[16] DAHL G E, EVANS N P, MOENTER S M, et al. The thyroid gland is required for reproductive neuroendocrine responses to photoperiod in the ewe[J]. Endocrinology, 1994, 135(1):10-15.
[17] HANON E A, LINCOLN G A, FUSTIN J M, et al. Ancestral TSH mechanism signals summer in a photoperiodic mammal[J]. Curr Biol, 2008, 18(15):1147-1152.
[18] EHRENKRANZ J, BACH P R, SNOW G L, et al. Circadian and circannual rhythms in thyroid hormones:determining the TSH and free T4 reference intervals based upon time of day, age, and sex[J]. Thyroid, 2015, 25(8):954-961.
[19] DARDENTE H, WYSE C A, BIRNIE M J, et al. A molecular switch for photoperiod responsiveness in mammals[J]. Curr Biol, 2010, 20(24):2193-2198.
[20] DUPRÉ S M, MIEDZINSKA K, DUVAL C V, et al. Identification of Eya3 and TAC1 as long-day signals in the sheep pituitary[J]. Curr Biol, 2010, 20(9):829-835.
[21] LEHMAN M N, COOLEN L M, GOODMAN R L. Minireview:kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus:a central node in the control of gonadotropin-releasing hormone secretion[J]. Endocrinology, 2010, 151(8):3479-3489.
[22] GOODMAN R L, JANSEN H T, BILLINGS H J, et al. Neural systems mediating seasonal breeding in the ewe[J]. J Neuroendocrinol, 2010, 22(7):674-681.
[23] DARDENTE H, LOMET D, ROBERT V, et al. Seasonal breeding in mammals:from basic science to applications and back[J]. Theriogenology, 2016, 86(1):324-332.
[24] WINTERMANTEL T M, CAMPBELL R E, PORTEOUS R, et al. Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility[J]. Neuron, 2006, 52(2):271-280.
[25] SINGH S R, HILEMAN S M, CONNORS J M, et al. Estradiol negative feedback regulation by glutamatergic afferents to A15 dopaminergic neurons:variation with season[J]. Endocrinology, 2009, 150(10):4663-4671.
[26] GOODMAN R L, MALTBY M J, MILLAR R P, et al. Evidence that dopamine acts via kisspeptin to hold GnRH pulse frequency in check in anestrous ewes[J]. Endocrinology, 2012, 153(12):5918-5927.
[27] SMITH J T, COOLEN L M, KRIEGSFELD L J, et al. Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain:a novel medium for seasonal breeding in the sheep[J]. Endocrinology, 2008, 149(11):5770-5782.
[28] GOODMAN R L, SINGH S R, VALENT M, et al. Glutamate input to A15 neurons may mediate estradiol negative feedback in anestrous ewes[J]. Front Neuroendocrinol, 2006, 27(1):65.
[29] GOODMAN R L, THIERY J C, DELALEU B, et al. Estradiol increases multiunit electrical activity in the A15 area of ewes exposed to inhibitory photoperiods[J]. Biol Reprod, 2000, 63(5):1352-1357.
[30] FORADORI C D, AMSTALDEN M, GOODMAN R L, et al. Colocalisation of dynorphin A and neurokinin B immunoreactivity in the arcuate nucleus and median eminence of the sheep[J]. J Neuroendocrinol, 2006, 18(7):534-541.
[31] RIZZOTI K, LOVELL-BADGE R. Pivotal role of median eminence tanycytes for hypothalamic function and neurogenesis[J]. Mol Cell Endocrinol, 2016, 445:7-13.
[32] UENOYAMA Y, PHENG V, TSUKAMURA H, et al. The roles of kisspeptin revisited:inside and outside the hypothalamus[J]. J Reprod Dev, 2016, 62(6):537-545.
[33] PINILLA L, AGUILAR E, DIEGUEZ C, et al. Kisspeptins and reproduction:physiological roles and regulatory mechanisms[J]. Physiol Rev, 2012, 92(3):1235-1316.
[34] OAKLEY A E, CLIFTON D K, STEINER R A. Kisspeptin signaling in the brain[J]. Endocr Rev, 2009, 30(6):713-743.
[35] WEEMS P, SMITH J, CLARKE I J, et al. Effects of season and estradiol on KNDy neuron peptides, colocalization with D2 dopamine receptors, and dopaminergic inputs, in the ewe[J]. Endocrinology, 2017, 158(4):831-841.
[36] MERKLEY C M, COOLEN L M, GOODMAN R L, et al. Evidence for changes in numbers of synaptic inputs onto KNDy and GnRH neurones during the preovulatory LH surge in the ewe[J]. J Neuroendocrinol, 2015, 27(7):624-635.
[37] MERKLEY C M, PORTER K L, COOLEN L M, et al. KNDy (kisspeptin/neurokinin B/dynorphin) neurons are activated during both pulsatile and surge secretion of LH in the ewe[J]. Endocrinology, 2012, 153(11):5406-5414.
[38] LEHMAN M N, LADHA Z, COOLEN L M, et al. Neuronal plasticity and seasonal reproduction in sheep[J]. Eur J Neurosci, 2010, 32(12):2152-2164.
[39] KLOSEN P, SÉBERT M E, RASRI K, et al. TSH restores a summer phenotype in photoinhibited mammals via the RF-amides RFRP3 and kisspeptin[J]. FASEB J, 2013, 27(7):2677-2686.
[40] SHINOMIYA A, SHIMMURA T, NISHIWAKI-OHKAWA T, et al. Regulation of seasonal reproduction by hypothalamic activation of thyroid hormone[J]. Front Endocrinol (Lausanne), 2014, 5:12.
[41] REVEL F G, MASSON-PÉVET M, PÉVET P, et al. Melatonin controls seasonal breeding by a network of hypothalamic targets[J]. Neuroendocrinology, 2009, 90(1):1-14.
[42] STEVENSON T J, BALL G F. Information theory and the neuropeptidergic regulation of seasonal reproduction in mammals and birds[J]. Proc Roy Sci B, 2011, 278(1717):2477-2485.
[43] NG L, LIU H, ST GERMAIN D L, et al. Deletion of the thyroid hormone-activating type 2 deiodinase rescues cone photoreceptor degeneration but not deafness in mice lacking type 3 deiodinase[J]. Endocrinology, 2017, 158(6):1999-2010.
[44] MAYWOOD E S, BITTMAN E L, HASTINGS M H. Lesions of the melatonin-and androgen-responsive tissue of the dorsomedial nucleus of the hypothalamus block the gonadal response of male Syrian hamsters to programmed infusions of melatonin[J]. Biol Reprod, 1996, 54(2):470-477.
[45] SONG C K, BARTNESS T J. The effects of anterior hypothalamic lesions on short-day responses in Siberian hamsters given timed melatonin infusions[J]. J Biol Rhythms, 1996, 11(1):14-26.
[46] SÁENZ DE MIERA C, HANON E A, DARDENTE H, et al. Circannual variation in thyroid hormone deiodinases in a short-day breeder[J]. J Neuroendocrinol, 2013, 25(4):412-421.
[47] YASUO S, YOSHIMURA T, EBIHARA S, et al. Photoperiodic control of TSH-β expression in the mammalian pars tuberalis has different impacts on the induction and suppression of the hypothalamo-hypopysial gonadal axis[J]. J Neuroendocrinol, 2010, 22(1):43-50.
[48] KAMPF-LASSIN A, PRENDERGAST B J. Acute downregulation of type Ⅱ and type Ⅲ iodothyronine deiodinases by photoperiod in peripubertal male and female Siberian hamsters[J]. Gen Comp Endocrinol, 2013, 193:72-78.
[49] SIMONNEAUX V, ANCEL C, POIREL V J, et al. Kisspeptins and RFRP-3 act in concert to synchronize rodent reproduction with seasons[J]. Front Neurosci, 2013, 7:22.
[50] ANSEL L, BOLBOREA M, BENTSEN A H, et al. Differential regulation of Kiss1 expression by melatonin and gonadal hormones in male and female Syrian hamsters[J]. J Biol Rhythms, 2010, 25(2):81-91.
[51] GREIVES T J, LONG K L, BURNS C M B, et al. Response to exogenous kisspeptin varies according to sex and reproductive condition in Siberian hamsters (Phodopus sungorus)[J]. Gen Comp Endocrinol, 2011, 170(1):172-179.
[52] GREIVES T J, KRIEGSFELD L, DEMAS G E. Exogenous kisspeptin does not alter photoperiod-induced gonadal regression in Siberian hamsters (Phodopus sungorus)[J]. Gen Comp Endocrinol, 2008, 156(3):552-558.
[53] UBUKA T, INOUE K, FUKUDA Y, et al. Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormone[J]. Endocrinology, 2012, 153(1):373-385.
[54] PERAGINE D E, POKAROWSKI M, MENDOZA V L, et al. RFamide-related peptide-3(RFRP-3) suppresses sexual maturation in a eusocial mammal[J]. Proc Natl Acad Sci U S A, 2017, 114(5):1207-1212.
[55] ANCEL C, BENTSEN A H, SÉBERT M E, et al. Stimulatory effect of RFRP-3 on the gonadotrophic axis in the male Syrian hamster:the exception proves the rule[J]. Endocrinology, 2012, 153(3):1352-1363.
[56] BAILEY A M, LEGAN S J, DEMAS G E. Exogenous kisspeptin enhances seasonal reproductive function in male Siberian hamsters[J]. Funct Ecol, 2017, 31(6):1220-1230.doi:10.1111/1365-2435.12846.

Research Progress on Neuroendocrinology Controlling Sheep Seasonal Reproduction

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